Verapamil – Verapamil DESCRIPTION
Calcium channel blocker
Verapamil belongs to the drug class of calcium channel blockers. The mechanism of action of it is that it prevents the penetration of calcium ions into vascular smooth muscle cells, causing it relaxes. This leads to an expansion of the lumen of the arteries and reduce blood pressure.
Application: Verapamil is used to treat hypertension, angina, and heart failure. Verapamil reduces the conductivity in the heart tissue, so it can also be used in cardiac arrhythmias, both for treatment and prevention.
Dosage. Verapamil administered in a dose of 180 to 480 mg per day. The daily dose can be divided into 1, 2 or 3 divided doses. Dose appoint a doctor. The drug is taken with food.
Interaction with drugs: the combination of verapamil with beta blockers may come a sharp slowdown in heartbeat. Acceptance of verapamil may increase blood levels of certain drugs: digoxin, carbamazepine and theophylline.
In some patients, verapamil may reduce the level of drug lithium, which is important to consider.
Pregnancy and breast-feeding. Verapamil crosses the placenta to the fetus and is excreted in breast milk. The effects on the fetus and newborn are unknown.
Side effects. Side effects of verapamil minor and temporary. It can cause dizziness, weakness due to slowing of the heart and reducing blood pressure. Among other effects may be swelling of the legs, skin rash, headache and constipation. In addition, verapamil may cause some deviation in liver function, but temporary.
Verapamil may reduce the heart rate. It can also reduce blood pressure too much (in rare cases). In addition, patients with compromised cardiac activity, it can cause heart failure.
German Heart Center – BERLIN
Cardiology Clinic NIDERBERG – Germany
CARDIOLOGY CENTER of MEDICINE – MOSCOW
EARLY DIAGNOSIS OF CARDIOVASCULAR DISEASES
Examination and treatment in GERMANY – Institute "DIAGNOSTIX"
AID IN THE TREATMENT –