The defeat of the pharynx in systemic blood diseases
The defeat of the pharynx in systemic blood diseases – Elite Treatment in Europe
ENT Diseases -2005
Infectious mononucleosis or lymphatic angina is an infectious disease agent which has not yet been found. Usually, infectious mononucleosis occurs in children and young adults.
For the disease characterized by:
- anginopodobnye changes in the pharynx
- adenosplenomegaliya and hematological changes – leukocytosis and a large number of atypical monocytes
- for serological studies revealed antibodies.
The incubation period lasts from 4-5 day sometimes up to 10 days. In early disease the body temperature rises to 38-40 C and kept for 5 days to 2 – 4 weeks, sometimes longer, sometimes with a period of improvement.
In the early and constant symptom of the disease is swelling of the lymph nodes at the beginning of the neck, and then get involved inguinal, axillary, abdominal and dr.Oni dense, painless on palpation, do not suppurate, regression exposed only at the end of the disease after normalization of body temperature, are sometimes enlarged for a longer period of time. The majority of patients with lymph nodes at the same time increasing the liver and spleen.
Changes in the throat usually occur when enlarged lymph nodes, and remind one of the banal angina – bluetongue, lacunary, fibrinous, less necrotizing. Raids on the tonsils remain for a long time, sometimes moving to the mucosa of the palatine arches, tongue, pharynx, resembling in this picture of diphtheria.
The most characteristic symptom is the appearance of the disease in the blood of a large number (60-80%) modified monocytes. ESR is usually raised.
For children ages characteristic feature is the involvement in the process early in the disease nasopharyngeal tonsils that causes nasal congestion, but without the usual discharge, nasal voice can make a shade. Another feature of the early age is to increase the tonsils. If the increase in the nasopharyngeal and palatine tonsils significant, there is difficulty breathing, stridor especially increases in the horizontal position. In this regard, sometimes there is a need for tracheostomy.
In rare cases, the disease is accompanied by hemorrhagic diathesis, skin purpura, bleeding from mucosal lesions of the central (serous meningitis, meningoencephalitis) and peripheral (polyneuritis, paresis of the facial nerve) nervous system.
Angina agranulotsitarnoy. The defeat of the tonsils with agranulocytosis is one of the characteristic symptoms of this disease. Agranulotsitarnoy hematopoiesis occurs in the reaction of various kinds of stimuli – infectious, toxic, radiation therapy or as a result of the defeat of blood-forming apparatus with systemic diseases of the blood. There are:
- subacute forms of agranulocytosis.
The disease begins with high fever. At the same time there are necrotic and ulcerative changes in the pharynx, in the tonsils, gums, and throat. In rare cases, destructive changes occur in the intestine, bladder and other organs. Necrotic process may extend into the soft tissue and bone.
Patients complain of severe pain in the throat, swallowing, excessive salivation, putrid breath. Overall condition is severe, septic temperature, aching joints, delirium may occur. In the blood, severe leukopenia, a few days the neutrophil count drops to zero.
In the treatment of the main effort is directed to the activation of the hematopoietic system and the fight against secondary infection.
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